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Delivered the "Cadence Advanced Technology Talk" on 6th September 2016.
Friday, September 9, 2016
Title of the Cadence ATT: Can a biologist fix a radio? — Challenges and opportunities in Computational Biology.
Summary: Historically biological science has involved study of living entities to explore their structure, function, evolution and classification. After the advent of computers biologists started using computing to answer relevant questions of biological origin, such as those pertaining to protein structures. Last few decades have witnessed an explosive growth in biological data from genomes, transcriptomes, proteomes, metabolomes and connectomes etc. This has led to a new era in computational biology with challenges for creating meaningful models of biological systems, their analysis and seeking for ways of their control. In this context, I shall invoke the metaphor of ‘biological system as a radio’ and ask: Can a biologist fix a radio? Towards answering this question, I will point out few pertinent challenges and opportunities in various domains including structural modeling, genomics, neuroscience, disease biology and pharmacology. Finally, I shall briefly present research from our lab around the themes of network medicine, side effects prediction, and our discovery of ‘negative (contrasting) food pairing’ in the Indian cuisine.
About Cadence Advanced Technology Talks : Cadence Advanced Technology Talk (ATT) aims at knowledge sharing at Cadence India. While the ATT session is held every month, once in a quarter Cadence invites technologists, researchers, industry leaders to present an ATT. In these talks expert present a topic in science or technology not directly related to their work in cadence. The hope is that these talks would broaden horizons and developments in the world of science and technology. These talks are held in Cadence Noida and beamed live to cadence Bangalore, Pune and Hyderabad.
The talk and exposure to challenges and opportunities in computational biology, that was presented by drawing an analogy between a radio and biological systems, was very well received by the audience. It was held at Cadence Noida and was beamed live to Cadence Bangalore, Pune and Hyderabad.